由于不规则的形状,正常和感染组织之间的各种尺寸和无法区分的边界,仍然是一种具有挑战性的任务,可以准确地在CT图像上进行Covid-19的感染病变。在本文中,提出了一种新的分段方案,用于通过增强基于编码器 - 解码器架构的不同级别的监督信息和融合多尺度特征映射来感染Covid-19。为此,提出了深入的协作监督(共同监督)计划,以指导网络学习边缘和语义的特征。更具体地,首先设计边缘监控模块(ESM),以通过将边缘监督信息结合到初始阶段的下采样的初始阶段来突出显示低电平边界特征。同时,提出了一种辅助语义监督模块(ASSM)来加强通过将掩码监督信息集成到稍后阶段来加强高电平语义信息。然后,通过使用注意机制来扩展高级和低电平特征映射之间的语义间隙,开发了一种注意融合模块(AFM)以融合不同级别的多个规模特征图。最后,在四个各种Covid-19 CT数据集上证明了所提出的方案的有效性。结果表明,提出的三个模块都是有希望的。基于基线(RESUNT),单独使用ESM,ASSM或AFM可以分别将骰子度量增加1.12 \%,1.95 \%,1.63 \%,而在我们的数据集中,通过将三个模型结合在一起可以上升3.97 \% 。与各个数据集的现有方法相比,所提出的方法可以在某些主要指标中获得更好的分段性能,并可实现最佳的泛化和全面的性能。
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为了增强神经网络的非线性并提高输入和响应变量之间的映射能力,激活函数在数据中扮演更复杂的关系和模式的重要作用。在这项工作中,提出了一种新颖的方法,仅通过向传统的激活功能(如Sigmoid,TanH和Relu)添加很少的参数来自适应地自定义激活函数。为了验证所提出的方法的有效性,提出了关于加速收敛性和提高性能的一些理论和实验分析,并基于各种网络模型进行一系列实验(例如AlexNet,Vggnet,Googlenet,Reset和DenSenet)和各种数据集(如Cifar10,CiFar100,MiniimAgenet,Pascal VOC和Coco)。为了进一步验证各种优化策略和使用场景中的有效性和适用性,还在不同的优化策略(如SGD,势头,adagrad,Adadelta和AdaDelta和Adam)之间实施了一些比较实验以及与分类和检测等不同的识别任务。结果表明,提出的方法非常简单,但在收敛速度,精度和泛化方面具有显着性能,它可以超越像雷丝和自适应功能等其他流行的方法,如在整体性能方面几乎所有实验。该代码公开可在https://github.com/huhaigen/aptove-custivation-操作系统上使用。该包装包括所提出的三种自适应激活功能,可用于可重复性目的。
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Accurate determination of a small molecule candidate (ligand) binding pose in its target protein pocket is important for computer-aided drug discovery. Typical rigid-body docking methods ignore the pocket flexibility of protein, while the more accurate pose generation using molecular dynamics is hindered by slow protein dynamics. We develop a tiered tensor transform (3T) algorithm to rapidly generate diverse protein-ligand complex conformations for both pose and affinity estimation in drug screening, requiring neither machine learning training nor lengthy dynamics computation, while maintaining both coarse-grain-like coordinated protein dynamics and atomistic-level details of the complex pocket. The 3T conformation structures we generate are closer to experimental co-crystal structures than those generated by docking software, and more importantly achieve significantly higher accuracy in active ligand classification than traditional ensemble docking using hundreds of experimental protein conformations. 3T structure transformation is decoupled from the system physics, making future usage in other computational scientific domains possible.
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Feature selection helps reduce data acquisition costs in ML, but the standard approach is to train models with static feature subsets. Here, we consider the dynamic feature selection (DFS) problem where a model sequentially queries features based on the presently available information. DFS is often addressed with reinforcement learning (RL), but we explore a simpler approach of greedily selecting features based on their conditional mutual information. This method is theoretically appealing but requires oracle access to the data distribution, so we develop a learning approach based on amortized optimization. The proposed method is shown to recover the greedy policy when trained to optimality and outperforms numerous existing feature selection methods in our experiments, thus validating it as a simple but powerful approach for this problem.
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Representing and synthesizing novel views in real-world dynamic scenes from casual monocular videos is a long-standing problem. Existing solutions typically approach dynamic scenes by applying geometry techniques or utilizing temporal information between several adjacent frames without considering the underlying background distribution in the entire scene or the transmittance over the ray dimension, limiting their performance on static and occlusion areas. Our approach $\textbf{D}$istribution-$\textbf{D}$riven neural radiance fields offers high-quality view synthesis and a 3D solution to $\textbf{D}$etach the background from the entire $\textbf{D}$ynamic scene, which is called $\text{D}^4$NeRF. Specifically, it employs a neural representation to capture the scene distribution in the static background and a 6D-input NeRF to represent dynamic objects, respectively. Each ray sample is given an additional occlusion weight to indicate the transmittance lying in the static and dynamic components. We evaluate $\text{D}^4$NeRF on public dynamic scenes and our urban driving scenes acquired from an autonomous-driving dataset. Extensive experiments demonstrate that our approach outperforms previous methods in rendering texture details and motion areas while also producing a clean static background. Our code will be released at https://github.com/Luciferbobo/D4NeRF.
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Deep neural networks are vulnerable to adversarial attacks. In this paper, we take the role of investigators who want to trace the attack and identify the source, that is, the particular model which the adversarial examples are generated from. Techniques derived would aid forensic investigation of attack incidents and serve as deterrence to potential attacks. We consider the buyers-seller setting where a machine learning model is to be distributed to various buyers and each buyer receives a slightly different copy with same functionality. A malicious buyer generates adversarial examples from a particular copy $\mathcal{M}_i$ and uses them to attack other copies. From these adversarial examples, the investigator wants to identify the source $\mathcal{M}_i$. To address this problem, we propose a two-stage separate-and-trace framework. The model separation stage generates multiple copies of a model for a same classification task. This process injects unique characteristics into each copy so that adversarial examples generated have distinct and traceable features. We give a parallel structure which embeds a ``tracer'' in each copy, and a noise-sensitive training loss to achieve this goal. The tracing stage takes in adversarial examples and a few candidate models, and identifies the likely source. Based on the unique features induced by the noise-sensitive loss function, we could effectively trace the potential adversarial copy by considering the output logits from each tracer. Empirical results show that it is possible to trace the origin of the adversarial example and the mechanism can be applied to a wide range of architectures and datasets.
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The traditional statistical inference is static, in the sense that the estimate of the quantity of interest does not affect the future evolution of the quantity. In some sequential estimation problems however, the future values of the quantity to be estimated depend on the estimate of its current value. This type of estimation problems has been formulated as the dynamic inference problem. In this work, we formulate the Bayesian learning problem for dynamic inference, where the unknown quantity-generation model is assumed to be randomly drawn according to a random model parameter. We derive the optimal Bayesian learning rules, both offline and online, to minimize the inference loss. Moreover, learning for dynamic inference can serve as a meta problem, such that all familiar machine learning problems, including supervised learning, imitation learning and reinforcement learning, can be cast as its special cases or variants. Gaining a good understanding of this unifying meta problem thus sheds light on a broad spectrum of machine learning problems as well.
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Machine learning-based segmentation in medical imaging is widely used in clinical applications from diagnostics to radiotherapy treatment planning. Segmented medical images with ground truth are useful for investigating the properties of different segmentation performance metrics to inform metric selection. Regular geometrical shapes are often used to synthesize segmentation errors and illustrate properties of performance metrics, but they lack the complexity of anatomical variations in real images. In this study, we present a tool to emulate segmentations by adjusting the reference (truth) masks of anatomical objects extracted from real medical images. Our tool is designed to modify the defined truth contours and emulate different types of segmentation errors with a set of user-configurable parameters. We defined the ground truth objects from 230 patient images in the Glioma Image Segmentation for Radiotherapy (GLIS-RT) database. For each object, we used our segmentation synthesis tool to synthesize 10 versions of segmentation (i.e., 10 simulated segmentors or algorithms), where each version has a pre-defined combination of segmentation errors. We then applied 20 performance metrics to evaluate all synthetic segmentations. We demonstrated the properties of these metrics, including their ability to capture specific types of segmentation errors. By analyzing the intrinsic properties of these metrics and categorizing the segmentation errors, we are working toward the goal of developing a decision-tree tool for assisting in the selection of segmentation performance metrics.
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Video Super-Resolution (VSR) aims to restore high-resolution (HR) videos from low-resolution (LR) videos. Existing VSR techniques usually recover HR frames by extracting pertinent textures from nearby frames with known degradation processes. Despite significant progress, grand challenges are remained to effectively extract and transmit high-quality textures from high-degraded low-quality sequences, such as blur, additive noises, and compression artifacts. In this work, a novel Frequency-Transformer (FTVSR) is proposed for handling low-quality videos that carry out self-attention in a combined space-time-frequency domain. First, video frames are split into patches and each patch is transformed into spectral maps in which each channel represents a frequency band. It permits a fine-grained self-attention on each frequency band, so that real visual texture can be distinguished from artifacts. Second, a novel dual frequency attention (DFA) mechanism is proposed to capture the global frequency relations and local frequency relations, which can handle different complicated degradation processes in real-world scenarios. Third, we explore different self-attention schemes for video processing in the frequency domain and discover that a ``divided attention'' which conducts a joint space-frequency attention before applying temporal-frequency attention, leads to the best video enhancement quality. Extensive experiments on three widely-used VSR datasets show that FTVSR outperforms state-of-the-art methods on different low-quality videos with clear visual margins. Code and pre-trained models are available at https://github.com/researchmm/FTVSR.
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Event cameras that asynchronously output low-latency event streams provide great opportunities for state estimation under challenging situations. Despite event-based visual odometry having been extensively studied in recent years, most of them are based on monocular and few research on stereo event vision. In this paper, we present ESVIO, the first event-based stereo visual-inertial odometry, which leverages the complementary advantages of event streams, standard images and inertial measurements. Our proposed pipeline achieves temporal tracking and instantaneous matching between consecutive stereo event streams, thereby obtaining robust state estimation. In addition, the motion compensation method is designed to emphasize the edge of scenes by warping each event to reference moments with IMU and ESVIO back-end. We validate that both ESIO (purely event-based) and ESVIO (event with image-aided) have superior performance compared with other image-based and event-based baseline methods on public and self-collected datasets. Furthermore, we use our pipeline to perform onboard quadrotor flights under low-light environments. A real-world large-scale experiment is also conducted to demonstrate long-term effectiveness. We highlight that this work is a real-time, accurate system that is aimed at robust state estimation under challenging environments.
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